3D-printed biomimetic bone implant polymeric composite scaffolds

نویسندگان

چکیده

Abstract This research introduced a new poly-ether-ether-ketone calcium hydroxyapatite (PEEK-cHAp) composite for convenient, fast, and inexpensive femur bone-implant scaffold with different lattice structures to mimic natural bone structure. Fused deposition modelling (FDM) was used print hybrid PEEK-based filament-bearing bioactive material suited developing cHAp. Using FDM, the same PEEK will be fabricated, depending on shape of fracture. The scaffolds were examined in vitro bioactivity by immersing them simulated bodily fluid (SBF) solution. Furthermore, cytotoxicity tests validated suitability materials employed create minimal toxicity scaffolds. After spreading nanoparticles grains, suggested spherical nanoparticle cell expanded over time. motif affected microstructure PEEK-cHAp terms grain size 3D shape. results established proposed optimum design suitable prospective implants, as required biomimetic artificial regeneration healing.

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ژورنال

عنوان ژورنال: The International Journal of Advanced Manufacturing Technology

سال: 2023

ISSN: ['1433-3015', '0268-3768']

DOI: https://doi.org/10.1007/s00170-023-11344-x